Environmental toxins accelerate Parkinson’s disease onset
نویسندگان
چکیده
منابع مشابه
Environmental toxins accelerate Parkinson's disease onset.
Several pathologic entities manifest as Parkinson syndrome (PS). The most common is the Lewy body disease also known as idiopathic PD.1 Most PD cases are sporadic and are believed to be caused by exogenous environmental factors.2,3 Autosomal dominant PD with a-synuclein gene mutation4 and autosomal recessive parkinsonism with parkin gene mutation5 have been reported in some families, but in gen...
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Maczulak AE. Pollution: Treating Environmental Toxins. New York, NY: Infobase Publishing; 2010. p. x+232. ISBN: 978-1-4381-2633-3
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Parkinson's disease (PD) is a chronic, progressive, disabling neurodegenerative disorder that begins in mid to late life and is characterized by motor impairment, autonomic dysfunction, and, in many, psychological and cognitive changes. Recent advances have helped delineate pathogenetic mechanisms, yet the cause of PD in most individuals is unknown. Although at least 15 genes and genetic loci h...
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Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by rigidity, resting tremor, and bradykinesia. It is produced by the selective loss of dopaminergic neurons within the substantia nigra pars compacta (SN). PD affects millions people worldwide being the second most common age-related neurodegenerative disorder with a prevalence of 1900 per 100,000 in people over ...
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People are exposed to various potentially toxic agents and conditions in their natural and occupational environments. These agents may be physical or chemical, may enter the human body through oral, inhalational, or transdermal routes, and may exert effects on all organ systems. Several well-known as well as lesser known associations exist between chronic kidney disease (CKD) and both environme...
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ژورنال
عنوان ژورنال: Neurology
سال: 2001
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.56.1.4